Greece, lenders resume talks on 8.1 billion euro bailout tranche

By Harry Papachristou

ATHENS (Reuters) - Greece and its international lenders resume talks to unlock 8.1 billion euros ($10.5 billion) of rescue loans on Monday after a two-week break in which the government almost collapsed over bailout-related firings at state broadcaster ERT.

Greek officials including Prime Minister Antonis Samaras have said they expect the talks to conclude successfully, despite setbacks to the country's privatization program and delays in public sector reform.

The stakes are high. If the talks fail, the IMF might have to withdraw from Greece's rescue to avoid violating its own funding rules. Athens also needs the cash to help redeem about 2.2 billion euros of bonds in August.

The installment is one of the last big cash injections Athens stands to get under its 240-billion euro bailout which expires at the end of 2014.

Finance Minister Yannis Stournaras will have his first meeting with representatives of the European Union, the European Central Bank and the International Monetary Fund, also known as the "troika", at 10 a.m. ET.

Samaras wants to wrap up the talks quickly for the funds to be released by the end of this month. He appointed two ardent reformers, Kyriakos Mitsotakis and Adonis Georgiadis, in a cabinet reshuffle last week to push for reforms at key ministries, civil administration and health.

"The lenders will give us trouble but less so than in previous reviews," one government aide told reporters on Sunday.

MISSING TARGETS

The government plans to ask creditors to lower this year's privatisation target of 2.6 billion euros after failing to find a buyer for natural gas company DEPA. [ID:nL5N0EN16J]

Athens has also missed a June deadline to place 12,500 state workers into a so-called "mobility scheme", under which they are transferred or dismissed within a year.

A shortfall of more than 1 billion euros has emerged at state-run health insurer EOPYY, meaning automatic spending cuts may have to be agreed to bring it on an even keel.

Athens and the troika are also at loggerheads over an unpopular property tax and over a possible reduction in a consumption tax for restaurants.

Samaras has ruled out imposing new austerity measures after losing a coalition partner in the ERT crisis, with his majority in the 300-seat parliament shrinking to just three votes.

More measures will be impossible to steer through parliament, analysts and lawmakers have said, after four years of austerity which plunged Greece into its deepest peace-time recession with the jobless rate at a record 27 percent.

The economic crisis has also boosted support for anti-bailout parties such as the ultra-right Golden Dawn.

According to Greek officials, the country has enough spare cash to offset any short-term slippages in the bailout plan.

Helped by tight spending, the budget deficit was about 3 billion euros smaller than expected in January-May, Stournaras said last week, adding that the country had also money left over in bank rescue fund HFSF.

But even if it clears the ongoing troika review, Athens will require additional help to stand on its own feet after the current bailout expires at the end of 2014.

According to provisional EU/IMF estimates for 2015-2016, Greece must plug a budget shortfall of about 4 billion euros and a funding gap of up to 9.5 billion. These estimates are to be updated later this year.

The euro zone has already pledged to shave off part of Greece's debt to make it sustainable in the long term. But it is still unclear how much debt will be written off and how.

(Editing by Gareth Jones)

Source: http://news.yahoo.com/greece-lenders-resume-talks-8-1-billion-euro-002341707.html

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Tahrir protesters show Egypt's Morsi the 'red card' | Morocco World ...

CAIRO, June 30, 2013 (AFP)

Thousands of demonstrators waved red cards in Tahrir Square Sunday to demand the resignation of Egypt?s Islamist President Mohamed Morsi, as the spirit of 2011?s revolution returned to the iconic Cairo protest venue.

?The people want the ouster of the regime!? protesters chanted ? the signature slogan of the uprising that ousted Hosni Mubarak and brought Morsi to power.

Jubilant men, women and children brandished red cards, blowing whistles and vuvuzelas and chanting ?Leave, Morsi!?

?This is the second revolution and Tahrir is the symbol of the revolution. The revolution will be launched from here,? said Ibrahim Hammouda, a carpenter who had came from the northern city of Damietta to join the protests.

In 2011, when hundreds of thousands of people took to the streets to end Mubarak?s authoritarian three-decade rule, they held up posters of regime figures with their faces crossed out.

This time, protesters are holding pictures of senior leaders of the Muslim Brotherhood, from which Morsi hails.

Morsi was elected a year ago in Egypt?s first ever free vote. But today, his critics accuse him of betraying the revolution by concentrating power in the hands of Islamist groups.

They accuse him of breaking his promise to be a president ?for all Egyptians? and letting the economy dive into free fall.

?I?m here because Morsi, who I voted for, betrayed me and did not keep his promises. Egypt will be liberated again from Tahrir Square,? said Mohammed Samir who travelled from the Nile Delta city of Mansura.

The Tahrir protest began hours before scheduled rallies and marches due to begin at 5:00 PM (1500 GMT), with several hundred people having spent the night in the square.

Street vendors sold flags and patriotic songs boomed from loudspeakers.

On the outskirts of the square, security checkpoints were manned by protesters in fluorescent vests under signs reading: ?No entry to the Brotherhood?.

?We are protecting the revolution from those who are against the revolution,?said protester Essam Ahmed.

On the other side of Cairo, in the Nasr City neighbourhood, thousands of pro-Morsi supporters gathered to show support for the president.

They insist that ousting an elected president would be a coup against democracy that they will not allow.

Egypt is deeply divided between Morsi?s mainly Islamist supporters and a broad-based opposition that also includes many deeply religious Muslims.

?Morsi, you hypocrite, you have split the people in two!? the protesters chanted in Tahrir.

The Muslim Brotherhood was long banned under Mubarak?s regime, but since the revolution they have dominated parliament, drafted a controversial constitution and been given key cabinet and local government positions.

?The Brotherhood did not continue our revolution and insisted on monopolising the state,? said Mohammed Abdel Wahab, a marketing manager from Cairo who came to Tahrir with his family.

Sunday?s protests were called by Tamarod (Arabic for Rebellion), a grassroots campaign that says it gathered more than 22 million signatures calling for Morsi to go and for a snap presidential election.

Source: http://www.moroccoworldnews.com/2013/06/96032/tahrir-protesters-show-egypts-morsi-the-red-card/

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Bulls cut ties with lead assistant coach Ron Adams

Posted by Inside Hoops

Jun 29

In a surprising move, the Bulls will not renew the contract of lead assistant coach Ron Adams.

Adams, in his second stint with the Bulls, came to Chicago following a successful run as Scott Brooks? lead assistant in Oklahoma City. A longtime friend of Tom Thibodeau?s, Adams left the Thunder to be closer to his family, who remained in the Chicago area for school reasons following Adams? first stint with the Bulls under Scott Skiles.

According to sources, general manager Gar Forman made the decision, not Thibodeau. Forman informed Adams on Friday.

Reported by K.C. Johnson of the?Chicago Tribune

Source: http://www.insidehoops.com/blog/?p=13616

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South Korea extends bidding on $7.3 billion fighter jet project: media

SEOUL (Reuters) - South Korea has extended bidding on a $7.3 billion (8.3 trillion won) fighter jet project after a second round of bidding ended on Friday with three aviation makers offering prices above the estimated cost, South Korea's news agency said.

South Korea opened the bidding on June 18 to import the country's 60 next-generation fighter jets between 2017 and 2021 and has since carried out about 30 bidding sessions, yet the offers were over the budget, South Korea's Yonhap News Agency said citing the state's Defense Acquisition Program Administration (DAPA) officials.

Lockheed Martin Corp's F-35A, Boeing Co's F-15SE and EADS' Eurofighter Typhoon are in the running to win the fighter competition.

"The bidding ended, and an additional bidding will resume on July 2," said Baek Yoon-hyeong, spokesman for the defense acquisition agency, according to Yonhap.

The project, called F-X, is South Korea's largest arms import ever.

(Reporting By Jane Chung; Editing by Michael Perry)

Source: http://news.yahoo.com/south-korea-extends-bidding-7-3-billion-fighter-074251604.html

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Kentucky Announces Online Gaming Settlement - WBKO

FRANKFORT, Ky. (AP) -- For the second time this month, Kentucky has announced an Internet gaming-related settlement, this time recovering $15 million in online gambling losses by Kentucky residents.

Gov. Steve Beshear's office said Kentucky filed a case against bwin.party in August 2010 and reached an agreement earlier this month.

Justice and Public Safety Cabinet spokeswoman Jennifer Brislin said the money will go into the state's General Fund. Another $6 million was earlier announced to be headed for Kentucky's General Fund from a settlement of unrelated federal court actions in New York and Maryland stemming from online gambling.

Beshear said in a statement that bwin.party was trying to comply with U.S. law and be known for "integrity and honesty in this industry."

(Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)

Source: http://www.wbko.com/home/headlines/Kentucky-Announces-Online-Gaming-Settlement-213585371.html

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Analysis: Supreme Court term ends with no easy way to label it (CNN)

Share With Friends: | | Politics - Top Stories Stories, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/315967464?client_source=feed&format=rss

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Rare Breed of Killer Whale May Be New Species

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Conn. hometown of Hernandez shocked at star's fall

HARTFORD, Conn. (AP) ? The murder case against former New England Patriots tight end Aaron Hernandez has led investigators to his hometown of Bristol, Conn., the working-class Hartford suburb where he began a meteoric rise that would carry him to the upper echelons of the NFL.

He is remembered as a fun-loving teenager at Bristol Central High School, where he followed in the footsteps of his older brother, D.J., who would star as a quarterback and tight end at the University of Connecticut.

Some recall him struggling with the death of his father, Dennis, in 2006, but remaining determined to become a pro athlete, spending hours working out before and after school. As Bristol police assist Massachusetts investigators, arresting one local man as a fugitive from justice, the community was left to ponder the fall of the hometown hero with the $40 million pro contract and a new family of his own.

A former high school teammate, Andrew Ragali, 24, said the troubled street hood he has seen portrayed on television is not the Aaron Hernandez he knew.

"You could maybe say he was immature, but he wasn't a gang-banger at all," Ragali said. "I think when he went to college things might have changed, hanging around with the wrong people, but in high school, he wasn't like that at all."

The 23-year-old Hernandez was arrested Wednesday at his mansion in North Attleborough, Mass., and accused of orchestrating the execution-style shooting of his friend, Odin Lloyd, allegedly because Lloyd had talked to the wrong people at a nightclub. He was denied bail at a hearing Thursday in a Massachusetts courtroom, where a prosecutor said a Hummer belonging to Hernandez turned up an ammunition clip matching the caliber of casings found at the scene of Lloyd's killing.

Hernandez's lawyer argued his client is not a risk to flee and the case against him is circumstantial.

On June 16, the night before the slaying, a prosecutor said, Hernandez texted two unidentified friends and asked them to hurry to Massachusetts from Connecticut. A few minutes later, he texted Lloyd to tell him he wanted to get together, the prosecutor said. Authorities say the three picked up Lloyd at around 2:30 a.m. June 17, drove him to an industrial park near Hernandez's home and shot him five times. They have not said who fired the shots.

New Britain State's Attorney Brian Preleski said Thursday that his office and Bristol police have been assisting investigators in Massachusetts and that Carlos Ortiz, 27, of Bristol, had been charged as a fugitive from justice. He waived extradition to Massachusetts and was being held on $1.5 million bail in Hartford.

Ortiz's public defender, Alfonzo Sirica, declined to comment about the case.

Massachusetts state police said Thursday night they were seeking another man, Ernest Wallace, in connection with Lloyd's killing. They issued an alert and wanted poster for Wallace, saying he was considered armed and dangerous, and sought the public's help in tracking down a silver or gray 2012 Chrysler 300 with Rhode Island license plates he was seen driving.

In Connecticut, Bristol is known to many as the home of ESPN, Otis Elevator and the Hernandez family.

Aaron and his brother each earned honors as the state's Gatorade high school player of the year, although they played several years apart at Bristol Central. Aaron would often visit his brother at UConn, and at one point verbally committed to follow D.J. and play for UConn himself. But Aaron became too big a star for the state school and signed instead to play at the University of Florida, a national powerhouse where he was an All-American.

Ragali recalled seeing Hernandez again, years after high school, at a Hartford bar. He described him as quieter, with more tattoos. But said he was very nice, asked about his family and took pictures with his girlfriend.

It was after his father's death that Hernandez began smoking marijuana and hanging out with a rough crowd, Hernandez's mother, Terri, told USA Today in 2009.

"The shock of losing his dad, there was so much anger," she said at the time.

Hernandez's mother works in the office at the local South Side elementary school, and other family members still live in Bristol.

"All I can say is that he will be cleared of all these charges in the end," she told the Bristol Press outside her home Wednesday. "Just let it play out until the end."

On Wednesday night, police searched a Bristol home and garage owned by Andres Valderrama, whom WFSB-TV identified as an uncle. A message was left at the home Thursday seeking comment.

The Patriots, who cut Hernandez following his arrest Wednesday, drafted him in 2010 and signed him last summer to five-year contract worth $40 million.

During the draft, one team said it wouldn't take him under any circumstances, and he was passed over by one club after another before New England picked him in the fourth round. Afterward, Hernandez said he had failed a drug test in college ? reportedly for marijuana ? and was up front with teams about it.

A Florida man filed a lawsuit last week claiming Hernandez shot him in the face after they argued at a strip club in February.

Hernandez became a father on Nov. 6 and said he intended to change his ways: "Now, another one is looking up to me. I can't just be young and reckless Aaron no more."

Hernandez could face life in prison if convicted.

___

Associated Press writer Michelle R. Smith in Fall River, Mass., contributed to this report.

Source: http://news.yahoo.com/conn-hometown-hernandez-shocked-stars-fall-064235101.html

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EPA: OH chemical reporting law doesn't trump feds

COLUMBUS, Ohio (AP) -- Federal environmental regulators are investigating a January chemical emergency at an Ohio oil well and asking why an inventory of the facility's chemicals wasn't available to local authorities, according to a letter released Wednesday by a coalition of activists.

The U.S. Environmental Protection Agency confirmed its investigation of the Jan. 16 incident near St. Marys in Auglaize County in an April 26 letter to the coalition. The alliance comprising the Center for Health, Environment & Justice, the Sierra Club, ProgressOhio and others said it received the letter May 31.

The groups had asked the federal EPA to review the St. Marys oil leak as well as alleged Clean Water Act violations in a separate Youngstown case to see if the Ohio Department of Natural Resources' oil and gas regulatory program is working effectively. The coalition proposes that the federal government take back its oversight responsibilities in the state.

Its complaint alleged that Ohio has been out of compliance with the federal Emergency Planning and Community Right-to-Know Act, or EPCRA, under which chemical inventories are to be publicly available, since 2001. In that year, state lawmakers passed a law "that essentially exempts the oil and gas industry operating in this state from requirements (of the federal law)," the activists said.

They pointed to the emergency near St. Marys to make their case. They said that when concentrated chemical odors were detected at the facility, local emergency responders were unable to access required chemical data that was supposed to be on file. The local newspaper was told the information was filed with the Ohio Department of Natural Resources, the groups said.

In his letter, U.S. EPA Superfund Division Director Richard Karl said that while an "alternate compliance method appears to be considered compliance" with state law, the Ohio law "does not designate (or attempt to designate) alternate compliance methods for the federal EPCRA law."

"Simply stated, the (state law) does not supersede (the federal one)," Karl wrote.

An official speaking for the Ohio Department of Natural Resources and the Ohio EPA said the impact of the federal government's finding is still being measured.

"The state is reviewing U.S. EPA's determination and we will soon be discussing this with the companies affected to ensure they are in compliance with their reporting obligations under state and federal law," spokesman Chris Abbruzzesse said in an email.

Teresa Mills, the nonprofit executive who authored the federal complaint, said she was surprised it took so long for the discrepancy to come to light ? and activists will keep a close eye on what happens.

"There are two options: The state of Ohio can correct the situation, or we can sue them," she said.

The coalition had earlier raised issues over oil and gas oversight in Ohio in light of recent federal indictments of Youngstown-area businessman Ben Lupo and an employee of his Hardrock Excavating LLC alleging that Lupo instructed the worker to illegally dump oil and gas wastes into a storm drain. The two have pleaded not guilty.

D&L Energy, where Lupo was a former president and shareholder, has been stripped of its operating permits as a result of that incident and recently failed in its attempt to challenge that action. The company is likely to appeal. The state also shut down the St. Marys well while the cause and extent of the January leak is investigated.

Activists question whether a state agency funded by the industry can impartially conduct the investigation ordered by Gov. John Kasich into whether potentially lax regulations led to the dumping incident alleged by federal prosecutors.

Source: http://news.yahoo.com/epa-oh-chemical-reporting-law-172526568.html

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AP Interview: UN Iraq rep urges exile cooperation

BAGHDAD (AP) ? The United Nations envoy to Iraq said Wednesday that residents of an Iranian dissident camp are denied freedom of movement by the exile group, and that efforts to relocate them outside Iraq are being stymied in part by lack of cooperation from the residents themselves.

Martin Kobler made the comments in an interview with The Associated Press in Baghdad as he prepares to leave the country at the end of his term. The U.N. has been involved in relocating members of the Mujahedeen-e-Khalq dissident group to a camp on the outskirts of the Iraqi capital while it works to resettle them abroad.

The MEK is the militant wing of a Paris-based Iranian opposition movement known as the National Council of Resistance of Iran that opposes Iran's clerical regime and has carried out assassinations and bombings there. They fear persecution if sent back to Iran.

About 3,100 MEK members live in Camp Liberty, a former U.S. military base near Baghdad airport. The Iraqi government wants the group's members out of the country. So do Iranian-backed Shiite militants, who have claimed responsibility for deadly rocket strikes on the camp.

Kobler acknowledged that a major problem in resettling camp residents is a shortage of countries willing to accept them. He repeated his call for U.N. member states, including the U.S., to do more.

"We do not have enough recipient countries. ... There is also reluctance from the side of the Liberty residents to cooperate with the UNHCR," he said, referring to the U.N. refugee agency.

Albania has agreed to take 210 camp residents, but only 71 have made the move so far. Germany has also offered to take 100 residents.

Kobler also cited concerns about what he called "human rights abuses inside Camp Liberty done by the MEK themselves."

Residents are not free to move between different sections of the camp without approval, and some are denied Internet and mobile phone access by MEK officials, he said. Medical treatment outside is also often blocked by the group, he alleged.

"There are, of course, MEK residents who probably would like to disassociate themselves from the MEK," he said. "Everybody who wants to go out of the camp ... should have the chance to do so."

The NCRI, the MEK's affiliated Paris-based group, has repeatedly criticized Kobler. He retains the backing of U.N. Secretary-General Ban Ki-moon, and was recently appointed the U.N. envoy and head of the U.N. peacekeeping mission in Congo.

NCRI spokesman Shahin Gobadi dismissed Kobler's comments as baseless and intended to "cover up the failure to provide minimum security provisions" at the camp.

"The only purpose they serve is they set the stage for more attacks," he said, insisting that residents cooperate with the U.N. Gobadi also charged that "Kobler has never been an impartial person and does not represent the values of the U.N."

Iraq gave foreign diplomats as well as journalists from AP and Iraq's state-run TV a rare glimpse of the camp in September. Diplomats on the tour described conditions as acceptable.

The MEK fought alongside Saddam Hussein's forces in the 1980-88 Iran-Iraq war, and several thousand of its members were given sanctuary at a facility known as Camp Ashraf near the Iranian border. The MEK renounced violence in 2001 and was removed from the U.S. terrorism list last year.

Iraq's Shiite-led government, which has close ties to Iran, considers the MEK a terrorist group. Iraqi security forces launched two deadly raids since 2009 on Camp Ashraf, and in 2012 most residents were moved to Camp Liberty, which is meant to be a temporary way station.

Ali al-Moussawi, a spokesman for Iraqi Prime Minister Nouri al-Maliki, said Baghdad also has concerns that MEK leaders are preventing residents from leaving.

"There is intimidation being practiced by some MEK leaders against their fellow people," al-Moussawi said. "Some MEK members are willing to leave the country, but they are being threatened by a minority preventing them."

The exiles say their new home is unsafe, and they want to return to Camp Ashraf. Several residents were killed in a Feb. 9 rocket strike on the camp, and two others died in a similar attack this month.

In another development Wednesday, Iraqi electoral officials said the Kurdish-backed al-Taakhi list won the largest single bloc of seats in provincial elections in the restive northern province of Ninevah. It claimed 11 of 39 provincial council seats up for grabs.

Ninevah borders Iraq's largely autonomous Kurdish region and has a sizable Kurdish minority. Many of the remaining seats went to Arab parties, with Iraqi parliament speaker Osama al-Nujaifi's Sunni Arab-backed United bloc coming in second, with eight seats.

Residents in Ninevah and neighboring Anbar province voted last week in local elections that were delayed due to security concerns.

Also Wednesday, Iraqi authorities said two policemen were killed in a bomb blast in the Ninevah provincial capital Mosul. Four others died in an explosion in a small cafe in Baghdad's Dora neighborhood, They spoke on condition of anonymity because they weren't authorized to release the information to journalists.

___

Associated Press writer Qassim Abdul-Zahra contributed reporting.

___

Follow Adam Schreck on Twitter at http://twitter.com/adamschreck

Source: http://news.yahoo.com/ap-interview-un-iraq-rep-urges-exile-cooperation-163517746.html

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Kinect-Powered Roaches Are an Army of Grossness

It's not very common to find an enthusiastic fan of motion-controlled gaming, but it's rarer to find an enthusiastic fan of roaches. But for the unlikely fan of both, researchers have developed the best(?) of both worlds: Kinect-controlled cockroaches.

The process itself is pretty straight-forward. Researchers attached some hardware to the roaches' antennae and administer a series of small shocks to trick them into thinking that they're butting up against walls. Meanwhile, a Kinect camera watches from above and tracks the roaches movement along a specified path. With that stereoscopic eye-in-the-sky, researchers are able to go completely hands-off and let a computer drive the roaches around all by itself, learning more about the finer points of roach-steering all the while.

Eventually, the hope is that these kind of roaches can be used in search-and-rescue situations. Assistant professor of electrical and computer engineering at NC State, Alper Bozkurt, put it this way:

We want to build on this program, incorporating mapping and radio frequency techniques that will allow us to use a small group of cockroaches to explore and map disaster sites. The autopilot program would control the roaches, sending them on the most efficient routes to provide rescuers with a comprehensive view of the situation.

Theoretically, the roaches could even be outfitted with microphones or other sensors, to allow people trapped in rubble communicated with their rescuers. But the prospect of being saved by an army of roaches might be enough to convince folks to find a way out of just about any disaster on their own. [NC State University via Wired]

Source: http://gizmodo.com/kinect-powered-roaches-are-an-army-of-grossness-584542221

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Scientists make wire of carbon, may sometime rival copper

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Microsoft launches Bing platform for developers

Microsoft wants developers to make Bing a central part of their apps, and it's powering that with a new developer platform unveiled today at Build. The Bing kit will let programmers tap the search engine's wealth of knowledge, providing direct information and translations when they're relevant. It should also grant access to natural interfaces, such as gestures, as well as real-world map data. Microsoft showed the platform at work in both Windows 8.1 and Windows Phone 8, so it's clear that developers who want Bing's resources won't be locked into any one device type.

Filed under: Internet, Software, Microsoft

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Remembering Antoni Gaud?, groundbreaking architect and modernist

A Google doodle Tuesday celebrates the legacy of?Antoni Gaud?, the Catalan architect.

By Matthew Shaer / June 25, 2013

The Google doodle today honors the work of Spanish architect Antoni Gaud?.

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The Google homepage today depicts six stylized images of monumental Spanish architecture, including the?Casa Batll?, in Barcelona, and the Casa Mila, in the?Eixample district of the same city. The doodle is an homage to the great Catalan architect ? and pioneering modernist ??Antoni Gaud?, who was born on June 25, 1852, in Reus, Catalonia, exactly 161 years ago Tuesday.?

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It is hard to understate Gaudi's impact on the world of modern art. UNESCO, which has placed several of Gaudi's buildings on its World Heritage List, from the Casa Bellesguard to the Casa Batll?, describes his contributions as helping shape 19th and 20th century?architecture and building technology:?

Gaud??s work exhibits an important interchange of values closely associated with the cultural and artistic currents of his time, as represented in el Modernisme of Catalonia. It anticipated and influenced many of the forms and techniques that were relevant to the development of modern construction in the 20th century.

Gaud? was apparently a relatively sickly child, but his convalescence, according to one online biography,?allowed him to spend "many hours contemplating nature, drawing lessons that he was to apply later in his architecture." In the late 1860s, he moved to Barcelona, initially to study teaching, but by 1873, he was enrolled in architecture school.?

Upon his graduation in 1878, Gaud? established his own architecture firm, and set about creating the works that would make his name. Perhaps his most famous early work is the Casa Vicens, a private residence in?the?Gr?cia?district of Barcelona. In the 1880s, he also completed work on the?G?ell Pavilions, which was named after?Eusebi G?ell,?Gaud?'s most steadfast patron.?

But as the website of the?Gaud? Experi?ncia museum puts it, it was in 1890 that Gaud? began to perfect "his understanding of architectural space and the applied arts, giving his work unique and unsuspected qualities that stood out from the other Modernist architecture of his day. These were Gaud?'s mature years in which a succession of master works appeared: Bellesguard Villa, Park G?ell, the restoration of Mallorca Cathedral, the church of the Col?nia G?ell, Casa Batll?, La Pedrera, and the Nativity fa?ade of the Sagrada Familia."

Gaud? received a commission to work on the?Sagrada Familia in 1883, and the grand church, with its sharp, perforated steeples and mosaic-dappled facade, became a kind of fixation for?Gaud?, who labored over the building for more than 40 long years.?

Gaud? died on June 10, 1926, after being hit by a tram in?Barcelona. Still, his legacy lives on, as does the Sagrada Familia, which remains unfinished even today, almost a century later. Earlier this year, in an interview with 60 Minutes, Gaud?'s?biographer Gijs van Hensbergen was asked to define the one thing that made?Gaud? a great artist.?

"The capacity to see space in a totally different way," Mr. van Hensbergen answered,?"to make space explode, to see a building as a sculpture rather than just as a place to live in or a roof over your head. He's someone who reinvented the language of architecture which no other architect has ever managed to do."?

For more tech news, follow us on?Twitter @venturenaut.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/1xvW64ia-fc/Remembering-Antoni-Gaudi-groundbreaking-architect-and-modernist

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A Professional Viner's Take On Instagram Video

I've already said my piece when it comes to the Vine vs. Instagram video debate, but what do other users have to say about it? Instagram and Vine user Meagan Cignoli posted the same stop-animation video on Vine and Instagram, and asked her followers which was better. She's a power user on both platforms, with nearly 10,000 followers on Instagram and nearly 200,000 followers on Vine.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/H4hE5uyNbUY/

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Microsoft and Oracle Team Up To Bring Java, Oracle Database, Linux and WebLogic Server To Azure And Windows Server

Ahead of their joint press conference later today, Microsoft and Oracle?announced a new partnership that will bring a number of Oracle products to Windows Server and the company's Azure cloud computing platform. These Oracle products include Java, Oracle Database and Oracle WebLogic Server.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/_4AvNyhUfR4/

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Razer's Blade a Small, Powerful Gaming Laptop - NYTimes.com

[unable to retrieve full-text content]Razer's 14-inch Blade gaming computer, which at two-thirds of an inch, claims to be the thinnest available, delivers high performance graphics at a high price ? $1800 to $2300, depending on the amount of memory.

Source: http://gadgetwise.blogs.nytimes.com/2013/06/25/razers-blade-a-small-powerful-gaming-laptop/

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Ten car bombs kill 39 in Iraqi capital

By Kareem Raheem

BAGHDAD (Reuters) - Ten car bombs exploded across the Iraqi capital on Monday, killing nearly 40 people in markets and garages on the evening of a Shi'ite Muslim celebration, police and medical sources said.

Some of the attacks targeted districts where Shi'ites were commemorating the anniversary of the birth of a revered Imam, but there also were explosions in mixed neighborhoods and districts with a high population of Sunnis.

The violence reinforced a growing trend since the start of the year, with more than 1,000 people killed in militant attacks in May alone, making it the deadliest month since the sectarian bloodletting of 2006-07.

Waleed, who witnessed one of Monday's explosions in which five people were killed in the Shi'ite stronghold of Sadr City, described a scene of chaos: "When the explosion happened, people ran in all directions."

"Many cars were burned, pools of blood covered the ground, and glass from car windows and vegetables were scattered everywhere."

Eight people were killed in two car bomb explosions in the central district of Karada, one of them in a car garage. Two car bombs exploded simultaneously near a market in the western district of Jihad, killing eight.

Separately, a bomb placed in a cafe in the northern city of Mosul killed five people, pushing Monday's death toll over 40.

Insurgents, including al Qaeda's Iraqi affiliate, have been recruiting from the country's Sunni minority, which feels sidelined following the U.S.-led invasion that toppled former dictator Saddam Hussein and empowered majority Shi'ites.

Since the withdrawal of U.S. troops in December 2011, critics say Shi'ite Prime Minister Nuri al-Maliki has consolidated his power over the security forces and judiciary, and has targeted several high-level Sunni leaders for arrest.

Sunnis took to the streets last December in protest against Maliki, but the demonstrations have thinned and are now being eclipsed by intensifying militant activity.

Sectarian tensions have been inflamed by the civil war in Syria, which is fast spreading into a region-wide proxy war, drawing in Shi'ite and Sunni fighters from Iraq and beyond to fight on opposite sides of the conflict.

Political deadlock in Baghdad has strained relations with Iraq's ethnic Kurds who run their own administration in the north of the country, and are at odds with the central government over land and oil.

(Reporting Kareem Raheem; Writing by Isabel Coles; Editing by Michael Roddy)

Source: http://news.yahoo.com/seven-bomb-blasts-kill-27-people-iraqi-capital-170556994.html

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WikiLeaks: Snowden going to Ecuador to seek asylum

A TV screen shows a news report of Edward Snowden, a former CIA employee who leaked top-secret documents about sweeping U.S. surveillance programs, at a shopping mall in Hong Kong Sunday, June 23, 2013. The former National Security Agency contractor wanted by the United States for revealing two highly classified surveillance programs has been allowed to leave for a "third country" because a U.S. extradition request did not fully comply with Hong Kong law, the territory's government said Sunday. (AP Photo/Vincent Yu)

A TV screen shows a news report of Edward Snowden, a former CIA employee who leaked top-secret documents about sweeping U.S. surveillance programs, at a shopping mall in Hong Kong Sunday, June 23, 2013. The former National Security Agency contractor wanted by the United States for revealing two highly classified surveillance programs has been allowed to leave for a "third country" because a U.S. extradition request did not fully comply with Hong Kong law, the territory's government said Sunday. (AP Photo/Vincent Yu)

FILE - In this June 21, 2013 file photo, a banner supporting Edward Snowden, a former CIA employee who leaked top-secret documents about sweeping U.S. surveillance programs, is displayed at Central, Hong Kong's business district. The Hong Kong government says Snowden wanted by the U.S. for revealing two highly classified surveillance programs has left for a "third country." The South China Morning Post reported Sunday, June 23, 2013 that Snowden was on a plane for Moscow, but that Russia was not his final destination. Snowden has talked of seeking asylum in Iceland. (AP Photo/Kin Cheung, File)

A TV screen shows a news report of Edward Snowden, a former CIA employee who leaked top-secret documents about sweeping U.S. surveillance programs, at a shopping mall in Hong Kong Sunday, June 23, 2013. The former National Security Agency contractor wanted by the United States for revealing two highly classified surveillance programs has been allowed to leave for a "third country" because a U.S. extradition request did not fully comply with Hong Kong law, the territory's government said Sunday. (AP Photo/Vincent Yu)

A TV screen shows a news report of Edward Snowden, a former CIA employee who leaked top-secret documents about sweeping U.S. surveillance programs, at a shopping mall in Hong Kong Sunday, June 23, 2013. The former National Security Agency contractor wanted by the United States for revealing two highly classified surveillance programs has been allowed to leave for a "third country" because a U.S. extradition request did not fully comply with Hong Kong law, the territory's government said Sunday. (AP Photo/Vincent Yu)

A TV screen shows a news report of Edward Snowden, a former CIA employee who leaked top-secret documents about sweeping U.S. surveillance programs, at a shopping mall in Hong Kong Sunday, June 23, 2013. The former National Security Agency contractor wanted by the United States for revealing two highly classified surveillance programs has been allowed to leave for a "third country" because a U.S. extradition request did not fully comply with Hong Kong law, the territory's government said Sunday. (AP Photo/Vincent Yu)

MOSCOW (AP) ? Edward Snowden, the former National Security Agency contractor wanted by the United States for revealing highly classified surveillance programs, flew to Russia on Sunday and planned to head to Ecuador to seek asylum, the South American country's foreign minister and the anti-secrecy group WikiLeaks said.

Foreign Minister Ricardo Patino said his government has received a request for asylum from Snowden. WikiLeaks, which is giving Snowden legal assistance, said his asylum request would be formally processed once he arrived in Ecuador, the same country that has already been sheltering the anti-secrecy group's founder Julian Assange in its London embassy.

Snowden arrived in Moscow on an Aeroflot flight shortly after 5 p.m. (1300gmt) Sunday after being allowed to leave Hong Kong, where he had been in hiding for several weeks after he revealed information on the highly classified spy programs.

Snowden was spending the night in Moscow's Sheremetyevo Airport and was booked on an Aeroflot flight to Cuba on Monday, the Russian news agencies ITAR-Tass and Interfax reported, citing unnamed airline officials. Aeroflot has no direct flights from Moscow to Quito, Ecuador; travelers would have to make connections in Paris, Rome or Washington, which could be problematic for Snowden.

Kristinn Hrafnsson, the WikiLeaks spokesman, told Britain's Sky News that Snowden would be meeting with diplomats from Ecuador in Moscow. WikiLeaks said he was being escorted by diplomats and legal advisers from the group.

The car of Ecuador's ambassador to Russia was parked outside the airport in the evening.

Assange, who has spent a year inside the Ecuadorean Embassy in London to avoid extradition to Sweden to face questioning about sex crime allegations, told the Sydney Morning Herald that WikiLeaks is in a position to help because it has expertise in international asylum and extradition law.

A U.S. official in Washington said Snowden's passport was annulled before he left Hong Kong, which could complicate but not thwart his travel plans. The U.S. official, who spoke on condition of anonymity for lack of authorization to discuss the matter, said that if a senior official in a country or airline ordered it, a country could overlook the withdrawn passport.

While Patino did not say if the asylum request would be accepted, Ecuador's President Rafael Correa has shown repeated willingness to irk the U.S. government and he has emerged as one of the leaders of Latin America's leftist bloc, along with Fidel and Raul Castro of Cuba and Venezuela's late President Hugo Chavez.

Both the United States and Britain protested his decision to grant asylum to Assange.

Critics have suggested that asylum for Assange might be aimed partly at blunting international criticism of Correa's own tough stance on critics and new restrictions imposed on the news media.

The White House said President Barack Obama has been briefed on Sunday's developments by his national security advisers.

Snowden's departure came a day after the United States made a formal request for his extradition and gave a pointed warning to Hong Kong against delaying the process of returning him to face trial in America.

The Department of Justice said only that it would "continue to discuss this matter with Hong Kong and pursue relevant law enforcement cooperation with other countries where Mr. Snowden may be attempting to travel."

The Hong Kong government said in a statement that Snowden left "on his own accord for a third country through a lawful and normal channel."

It acknowledged the U.S. extradition request, but said U.S. documentation did not "fully comply with the legal requirements under Hong Kong law." It said additional information was requested from Washington, but since the Hong Kong government "has yet to have sufficient information to process the request for provisional warrant of arrest, there is no legal basis to restrict Mr. Snowden from leaving Hong Kong."

The statement said Hong Kong had informed the U.S. of Snowden's departure. It added that it wanted more information about alleged hacking of computer systems in Hong Kong by U.S. government agencies which Snowden had revealed.

Hong Kong's decision to let Snowden go on a technicality appears to be a pragmatic move aimed at avoiding a drawn out extradition battle. The action swiftly eliminates a geopolitical headache that could have left Hong Kong facing pressure from both Washington and Beijing.

Hong Kong, a former British colony, has a high degree of autonomy and is granted rights and freedoms not seen on mainland China, but under the city's mini constitution Beijing is allowed to intervene in matters involving defense and diplomatic affairs. Hong Kong has an extradition treaty with the U.S., but the document has some exceptions, including for crimes deemed political.

Russian officials have given no indication that they have any interest in detaining Snowden or any grounds to do so. Foreign Minister Sergey Lavrov has said that Russia would be willing to consider granting asylum if Snowden were to make such a request. Russia and the United States have no extradition treaty that would oblige Russia to hand over a U.S. citizen at Washington's request.

The Cuban government had no comment on Snowden's movements or reports he might use Havana as a transit point.

Snowden's latest travels came as the South China Morning Post released new allegations from the former NSA contractor that U.S. hacking targets in China included the nation's cellphone companies and two universities hosting extensive Internet traffic hubs.

He told the newspaper that "the NSA does all kinds of things like hack Chinese cellphone companies to steal all of your SMS data." It added that Snowden said he had documents to support the hacking allegations, but the report did not identify the documents. It said he spoke to the newspaper in a June 12 interview.

With a population of more than 1.3 billion, China has massive cellphone companies. China Mobile is the world's largest mobile network carrier with 735 million subscribers, followed by China Unicom with 258 million users and China Telecom with 172 million users.

Snowden said Tsinghua University in Beijing and Chinese University in Hong Kong, home of some of the country's major Internet traffic hubs, were targets of extensive hacking by U.S. spies this year. He said the NSA was focusing on so-called "network backbones" in China, through which enormous amounts of Internet data passes.

The Chinese Foreign Ministry said it was aware of the reports of Snowden's departure from Hong Kong to Moscow but did not know the specifics. It said the Chinese central government "always respects" Hong Kong's "handling of affairs in accordance with law." The Foreign Ministry also noted that it is "gravely concerned about the recently disclosed cyberattacks by relevant U.S. government agencies against China."

China's state-run media have used Snowden's allegations to poke back at Washington after the U.S. had spent the past several months pressuring China on its international spying operations.

A commentary published Sunday by the official Xinhua News Agency said Snowden's disclosures of U.S. spying activities in China have "put Washington in a really awkward situation."

"Washington should come clean about its record first. It owes ... an explanation to China and other countries it has allegedly spied on," it said. "It has to share with the world the range, extent and intent of its clandestine hacking programs."

____

Hui reported from London. Kelvin Chan in Hong Kong, Paul Haven in Havana, Gonzalo Solano in Quito, Ecuador, and Matthew Lee, Anne Flaherty and Julie Pace in Washington contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-06-23-NSA-Surveillance-Snowden/id-6231312173e14d80ad3b11db5fb7b972

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Best?and worst?states to be a kid

The Kids Count report ranks the well-being of kids in the U.S. (AP)There?s good news for the children of Mississippi; their state is no longer the worst place to be a kid. That?s because a new set of annual rankings on children?s welfare says New Mexico has dethroned Mississippi's perennial hold on the bottom ranking of the Kids Count list.

For the past 24 years, the Annie E. Casey Foundation has used a series of 16 indicators to rank the well-being of children in all 50 U.S. states. This year?s edition is the first to not place Mississippi at 50 out of 50 on the list, citing gains in health and education. However, Mississippi is still No. 49 on the list.

The foundation also noted that a third of Mississippi?s children continue to live in poverty. By comparison, 13 percent of New Hampshire?s children are listed as living at or below the poverty level.

On the opposite end of the spectrum, New Hampshire, Vermont and Massachusetts finished at the top of the children?s well-being list.

?While we are not where we need to be, the fact that our child and teen death rate, along with some decrease in the percentage of children without health insurance has been helpful,? Mississippi Kids Count Director Linda Southward told the Northeast Mississippi Daily Journal.

There also appears to be an overall improving trend in the South. Louisiana, which was 46th on the list, is the only other Southern state to finish in the bottom five. However, the Southwest has fared less well?three of the bottom-five states are New Mexico, Arizona and Nevada.

Southward said Mississippi saw its gains through improvement in the number of children enrolled in preschool and general student improvements in math for eighth-graders and reading for fourth-graders. Overall, Mississippi was 48th in the Kids Count educational rankings. However, it did not see any economic gains during the same period, continuing to rank 50th on that list.

?The evidence is clear?we help children by helping families,? Southward said. ?The importance of quality child care, fully funding education opportunities for children and promoting evidence-based practices, underscored by economic development, is crucial to continued outcomes.?

This year?s rankings were based on national data compiled between 2005-2011. For those years, Mississippi?s numbers improved across eight of the 16 statistical areas measured. Overall, the United States improved in 10 of the categories during the same period.

Mississippi saw other gains on the list, including a drop in teen pregnancy rates and a drop in its infant mortality rate that has shown an improvement outpacing the national average.

?We are still woefully behind the country in reading proficiencies, and the high percentage of high school students not graduating on time continues to be of concern,? Southward said.

Source: http://news.yahoo.com/blogs/sideshow/mississippi-no-longer-worst-state-kid-200921073.html

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A wakeup call heeded as 'Mad Men' season ends

NEW YORK (AP) ? We have now left Don Draper in a state ripe for rehab ? both literally and figuratively.

Airing Sunday night, the season finale of "Mad Men" found its troubled hero reeling from one bender too many.

"I realized it's gotten out of control," he told his wife, Megan, after a night in a drunk tank after punching out a priest who ticked him off in a bar. "I've gotten out of control," he added.

No kidding.

In its penultimate sixth season spanning the turbulent year of 1968, this AMC drama charted Draper's downward spiral, cheating on his wife with a downstairs neighbor and wreaking havoc at the Manhattan ad agency where he used to be golden.

Until now a charismatic master of pretense, Draper by season's end acknowledged what every "Mad Men" viewer already knew: Don's fabled mojo had failed him. But he seemed prepared to take corrective action.

Did he have a lot of choice? In a startling scene, Draper (series star Jon Hamm) was summoned to a meeting for some bad news: He was being sidelined at Sterling Cooper & Partners.

That is, Draper was ordered to "take some time off and regroup," in the pointed words of fellow partner Roger Sterling (John Slattery).

This expulsion came after a powwow days earlier with the bosses of a possible new client, Hershey's Chocolate, where the silver-tongued Draper did what he does best: infusing the product with his own seductive myths.

Don had the Hershey execs spellbound with a heart-tugging recollection of his father rewarding him with a Hershey bar for mowing the lawn.

"Hershey's is the currency of affection," he rhapsodized. "It's the childhood symbol of love."

But then, as if suffering a crisis of conscience, he pulled a one-eighty. Always a master of revisionist history, Draper revised his pitch from fantasy to truth: He was actually an orphan raised in a whorehouse, he revealed, where, trying to capture the experience of a normal kid, he would eat a Hershey bar he got from one of the girls "who made me go through her john's pockets while they screwed."

Don's eyes moistened, his voice sank to a whisper in a scene that should clinch Hamm his long-withheld Emmy.

"Do you want to advertise THAT?" asked a puzzled Hershey exec.

"If I had my way, you would NEVER advertise," Draper answered. "And you shouldn't have someone like me telling that boy" ? every happy, normal boy with a father who loves him ? "what a Hershey bar is. He already knows."

It was a startlingly awkward moment for the agency partners, but a galvanizing moment of truth for Don.

This step toward redemption, if that's what it turns out to be, was likely triggered two episodes ago, when his teenage daughter Sally found him cheating on his wife. Sally was traumatized.

So was Draper at being discovered by her.

"It's the worst thing that ever happened to him," said "Mad Men" creator Matthew Weiner in a recent interview. "His pain and guilt and shame are indescribable."

It was the wakeup call Don was long overdue for.

"We discovered a lot about Don this year as he realized who he really is," Weiner said. "And we discovered that he doesn't want to be that way."

No wonder.

On the finale, he torpedoed the romance of longtime colleague Peggy Olson (Elisabeth Moss) with her new love, agency partner Ted Chaough (Kevin Rahm). Don facilitated Ted's wish to move to California with his family to separate himself from Peggy, breaking off their affair and thereby saving his marriage.

At the same time, Don put his own marriage in hock by breaking his earlier promise to Megan for them, not Ted, to make the move to California for the agency and make a fresh start of their own.

"The agency decided it," Don lied when telling her the change of plans.

Even with no inkling he had routinely betrayed her with a mutual friend who lived just one floor away, Megan had long felt he was growing more remote. His reneging on the move west with her was the last straw.

"You want to be alone with your liquor and your ex-wife and your screwed-up kids!" she seethed as she walked out the door.

Megan's words were an eerie echo of last season's conclusion, with Draper planted at a posh Manhattan bar and approached by a beautiful woman who asked, "Are you alone?" Viewers never learned what happened then.

What will happen next?

Painful recognition appears to be propelling "Mad Men" toward its final season, while leaving viewers to ponder how ? or if ? Don will patch up his marriage, his career and his relationship with Sally.

Weiner, who resumes the writing process soon, insisted many questions are yet to be settled.

On the other hand, he has had the final moments of the show in mind for years, he said, though he took pains to tamp down viewer expectations.

"There's no big reveal coming," Weiner declared. "What to leave the audience with is what I've been thinking about, and I have an image. But I don't want to oversell it. Honestly, I'm in denial about the show ending. But we'll get to it when we get to it ? and then it will be on the air."

In the meanwhile, viewers are left with this image: Don Draper's newly discombobulated life. But signaling hope for both him and the audience, he seems to understand he can't just charm his way out of it.

___

Online:

http://www.amctv.com

___

EDITOR'S NOTE ? Frazier Moore is a national television columnist for The Associated Press. He can be reached at fmoore@ap.org and at http://www.twitter.com/tvfrazier

Source: http://news.yahoo.com/wakeup-call-heeded-mad-men-season-ends-080457293.html

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Obama to unveil climate plan in Tuesday speech

WASHINGTON (AP) ? President Barack Obama is preparing to unveil his long-awaited national plan to combat climate change in a major speech, he announced on Saturday.

"There's no single step that can reverse the effects of climate change," Obama said in an online video released by the White House. "But when it comes to the world we leave our children, we owe it to them to do what we can."

People consulting with White House officials on Obama's plan, to be unveiled Tuesday at Georgetown University, say they expect him to put forth regulations on heat-trapping gases emitted by existing coal-fired power plans. They were not authorized to disclose details about the plan ahead of the announcement and requested anonymity.

Environmental groups have been pleading with Obama to take that step, but the administration has said it's focused first on controls on new power plants. The Environmental Protection Agency, using its authority under the Clean Air Act, has already proposed controls on new plants, but the rules have been delayed ? to the chagrin of states and environmental groups threatening to sue over the delays.

An administration official said last week that Obama was still weighing whether to include existing plants in the climate plan. The official wasn't authorized to comment by name and requested anonymity.

The White House wouldn't disclose any details Saturday about what steps Obama may call for. But his senior energy and climate adviser, Heather Zichal, said last week that controls on greenhouse gas emissions from power plants would be a major focus. She also said the plan would boost energy efficiency of appliances and buildings, plus expand renewable energy.

Putting a positive spin on a contentious partisan issue, Obama said the U.S. is uniquely poised to deal with the serious challenges posed by climate change. He said American scientists and engineers would have to design new fuels and energy sources, and workers will have to adapt to a clean energy economy.

"We'll need all of us, as citizens, to do our part to preserve God's creation for future generations," Obama said.

Environmental groups have for months been pushing Obama to make good on a threat he issued to lawmakers in February in his State of the Union address: "If Congress won't act soon to protect future generations, I will." Obama's move to take the matter into his own hands appears to reflect a growing consensus that opposition in Congress is too powerful for any meaningful, sweeping climate legislation to pass anytime soon.

"They shouldn't wait for Congress to act, because they'll be out of office by the time that Congress gets its act together," Rep. Henry Waxman, the top Democrat on the House Energy and Commerce Committee, said in an interview.

Environmental groups applauded the announcement that Obama was finally releasing a plan for executive action, but made clear they want to see firm proposals ? including controls for existing power plants.

"Combating climate change means curbing carbon pollution ? for the first time ever ? from the biggest single source of such dangerous gases: our coal-fired power plants," said Frances Beinecke, president of the National Resources Defense Council. "We stand ready to help President Obama in every way we can."

Another key issue hanging over the announcement ? but unlikely to be mentioned on Tuesday ? is Keystone XL, a pipeline that would carry oil extracted from tar sands in western Canada to refineries along the Texas Gulf Coast. A concerted campaign by environmental activists to persuade Obama to nix the pipeline appears to be an uphill battle. The White House insists the State Department is making the decision independently.

Obama's speech on Tuesday will come the day before he leaves for a weeklong trip to three African nations.

___

Online:

http://www.youtube.com/watch?v=gcL3_zzgWeU

___

Reach Josh Lederman on Twitter at http://twitter.com/joshledermanAP

Source: http://news.yahoo.com/obama-unveil-climate-plan-tuesday-speech-191840941.html

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The genome's 3-D structure shapes how genes are expressed

June 23, 2013 ? Scientists from Australia and the United States bring new insights to our understanding of the three-dimensional structure of the genome, one of the biggest challenges currently facing the fields of genomics and genetics. Their findings are published in Nature Genetics, online today.

Roughly 3 metres of DNA is tightly folded into the nucleus of every cell in our body. This folding allows some genes to be 'expressed', or activated, while excluding others.

Dr Tim Mercer and Professor John Mattick from Sydney's Garvan Institute of Medical Research and Professor John Stamatoyannopoulos from Seattle's University of Washington analysed the genome's 3D structure, at high resolution.

Genes are made up of 'exons' and 'introns' - the former being the sequences that code for protein and are expressed, and the latter being stretches of noncoding DNA in-between. As the genes are copied, or 'transcribed', from DNA into RNA, the intron sequences are cut or 'spliced' out and the remaining exons are strung together to form a sequence that encodes a protein. Depending on which exons are strung together, the same gene can generate different proteins.

Using vast amounts of data from the ENCODE project*, Dr Tim Mercer and colleagues have inferred the folding of the genome, finding that even within a gene, selected exons are easily exposed.

"Imagine a long and immensely convoluted grape vine, its twisted branches presenting some grapes to be plucked easily, while concealing others beyond reach," said Dr Mercer. "At the same time, imagine a lazy fruit picker only picking the grapes within easy reach.

"The same principle applies in the genome. Specific genes and even specific exons, are placed within easy reach by folding."

"Over the last few years, we've been starting to appreciate just how the folding of the genome helps determine how it's expressed and regulated,"

"This study provides the first indication that the three-dimensional structure of the genome can influence the splicing of genes."

"We can infer that the genome is folded in such a way that the promoter region -- the sequence that initiates transcription of a gene -- is located alongside exons, and they are all presented to transcription machinery."

"This supports a new way of looking at things, one that the genome is folded around transcription machinery, rather than the other way around. Those genes that come in contact with the transcription machinery get transcribed, while those parts which loop away are ignored."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/459JXnr-9hM/130623145058.htm

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